Siew, Shi Yong: search on Z-Library

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1

Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development

Caillet-Saguy, Célia, Lim, Siew Pheng, Shi, Pei-Yong, Lescar, Julien, Bressanelli, Stéphane

Journal:

Antiviral Research

Year:

2014

Language:

english

File:

PDF, 2.44 MB

english, 2014

2

West Nile Virus Drug Discovery

Lim, Siew, Shi, Pei-Yong

Journal:

Year:

2013

Language:

english

File:

PDF, 789 KB

english, 2013

3

Strategies for development of dengue virus inhibitors

Christian G. Noble, Yen-Liang Chen, Hongping Dong, Feng Gu, Siew Pheng Lim, Wouter Schul, Qing-Yin Wang, Pei-Yong Shi

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 1014 KB

english, 2010

4

Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2′-O methyltransferase activity in dengue virus

Ka Yan Chung, Hongping Dong, Alexander Theodore Chao, Pei-Yong Shi, Julien Lescar, Siew Pheng Lim

Journal:

Year:

2010

Language:

english

File:

PDF, 817 KB

english, 2010

5

Biochemical and genetic characterization of dengue virus methyltransferase

Hongping Dong, David C. Chang, Xuping Xie, Ying Xiu Toh, Ka Yan Chung, Gang Zou, Julien Lescar, Siew Pheng Lim, Pei-Yong Shi

Journal:

Year:

2010

Language:

english

File:

PDF, 2.29 MB

english, 2010

6

Ten years of dengue drug discovery: Progress and prospects

Lim, Siew Pheng, Wang, Qing-Yin, Noble, Christian G., Chen, Yen-Liang, Dong, Hongping, Zou, Bin, Yokokawa, Fumiaki, Nilar, Shahul, Smith, Paul, Beer, David, Lescar, Julien, Shi, Pei-Yong

Journal:

Antiviral Research

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

7

Generating self-accelerating Airy beams using a digital micromirror device

Xu, Qinwei, Wang, Yongdong, Siew, Shi Yong, Lin, Jiao, Zhang, Yilei

Journal:

Applied Physics B: Lasers and Optics

Year:

2014

Language:

english

File:

PDF, 653 KB

english, 2014

8

Investigating the ICT Needs of ‘Digital Natives’ in the Learning of English in a Public University in East Malaysia

Lee, Kean Wah, Thang, Siew Ming, Tan, Choon Keong, Ng, Shi Ing, Yoon, Sook Jhee, Chua, Yong Wei, Nadin, Shelly Shirlenna

Journal:

Procedia - Social and Behavioral Sciences

Year:

2014

Language:

english

File:

PDF, 322 KB

english, 2014

9

The dengue virus NS5 protein as a target for drug discovery

Lim, Siew Pheng, Noble, Christian G., Shi, Pei-Yong

Journal:

Antiviral Research

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

10

Characterization and mechanical performance study of silk/PVA cryogels: towards nucleus pulposus tissue engineering

Neo, Puay Yong, Shi, Pujiang, Goh, James Cho-Hong, Toh, Siew Lok

Journal:

Biomedical Materials

Year:

2014

Language:

english

File:

PDF, 1.98 MB

english, 2014

11

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

Zhao, Yongqian, Soh, Tingjin Sherryl, Zheng, Jie, Chan, Kitti Wing Ki, Phoo, Wint Wint, Lee, Chin Chin, Tay, Moon Y. F., Swaminathan, Kunchithapadam, Cornvik, Tobias C., Lim, Siew Pheng, Shi, Pei-Yong

Journal:

Year:

2015

Language:

english

File:

PDF, 2.34 MB

english, 2015

12

2′-O Methylation of Internal Adenosine by Flavivirus NS5 Methyltransferase

Dong, Hongping, Chang, David C., Hua, Maggie Ho Chia, Lim, Siew Pheng, Chionh, Yok Hian, Hia, Fabian, Lee, Yie Hou, Kukkaro, Petra, Lok, Shee-Mei, Dedon, Peter C., Shi, Pei-Yong, Kuhn, Richard J.

Journal:

Year:

2012

Language:

english

File:

PDF, 830 KB

english, 2012

13

Flexibility of NS5 Methyltransferase-Polymerase Linker Region is Essential for Dengue virus Replication

Zhao, Yongqian, Soh, Tingjin Sherryl, Chan, Kitti Wing Ki, Fung, Sarah Suet Yin, Swaminathan, Kunchithapadam, Lim, Siew Pheng, Shi, Pei-Yong, Huber, Thomas, Lescar, Julien, Luo, Dahai, Vasudevan, Subh

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 1.87 MB

english, 2015

14

Enhancing Analysis of Cells and Proteins by Fluorescence Imaging on Silk-Based Biomaterials: Modulating the Autofluorescence of Silk

Neo, Puay Yong, Tan, Daryl Jian-An, Shi, Pujiang, Toh, Siew Lok, Goh, James Cho-Hong

Journal:

Tissue Engineering Part C Methods

Year:

2015

Language:

english

File:

PDF, 2.26 MB

english, 2015

15

Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

Zhao, Yongqian, Soh, Tingjin Sherryl, Lim, Siew Pheng, Chung, Ka Yan, Swaminathan, Kunchithapadam, Vasudevan, Subhash G., Shi, Pei-Yong, Lescar, Julien, Luo, Dahai

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.47 MB

english, 2015

16

A Conserved Pocket in the Dengue Virus Polymerase Identified Through Fragment-Based Screening

Noble, Christian G., Lim, Siew Pheng, Arora, Rishi, Yokokawa, Fumiaki, Nilar, Shahul, Seh, Cheah Chen, Wright, S. Kirk, Benson, Timothy E., Smith, Paul W., Shi, Pei-Yong

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 3.53 MB

english, 2016

17

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase From a Fragment Hit Using Structure-Based Drug Design

Yokokawa, Fumiaki, Nilar, Shahul, Noble, Christian G., Lim, Siew Pheng, Rao, Ranga, Tania, Stefani, Wang, Gang, Lee, Gladys, Hunziker, Juerg, Karuna, Ratna, Manjunatha, Ujjini H., Shi, Pei-Yong, Smith

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

18

Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5′-Capped Octameric RNA

Yap, Li Jian, Luo, Dahai, Chung, Ka Yan, Lim, Siew Pheng, Bodenreider, Christophe, Noble, Christian, Shi, Pei-Yong, Lescar, Julien, Lindenbach, Brett

Journal:

Year:

2010

Language:

english

File:

PDF, 539 KB

english, 2010

19

NS5 from Dengue Virus Serotype 2 Can Adopt a Conformation Analogous to That of Its Zika Virus and Japanese Encephalitis Virus Homologues

El Sahili, Abbas, Soh, Tingjin Sherryl, Schiltz, Jonas, Gharbi-Ayachi, AÃ¯cha, Seh, Cheah Chen, Shi, Pei-Yong, Lim, Siew Pheng, Lescar, Julien, Heise, Mark T.

Journal:

Journal of Virology

Year:

2019

File:

PDF, 3.70 MB

2019